An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent

  • Nicky J Willis,
  • Elliott D Bayle,
  • George Papageorgiou,
  • David Steadman,
  • Benjamin N Aktinson,
  • William Mahy and
  • Paul V Fish
Published 16 Jul 2019
Beilstein Arch. 2019, 201970. doi:10.3762/bxiv.2019.70.v1

A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light

  • Xavier Gómez-Santacana,
  • Sabrina M. de Munnik,
  • Tamara A. M. Mocking,
  • Niels J. Hauwert,
  • Shanliang Sun,
  • Prashanna Vijayachandran,
  • Iwan J. P. de Esch,
  • Henry F. Vischer,
  • Maikel Wijtmans and
  • Rob Leurs
Published 15 Jul 2019
Beilstein Arch. 2019, 201969. doi:10.3762/bxiv.2019.69.v1

Photochromic diarylethene with turn-off fluorescent switching property

  • Luna Kono,
  • Yuma Nakagawa,
  • Ayako Fujimoto,
  • Ryo Nishimura,
  • Yohei Hattori,
  • Toshiki Mutai,
  • Nobuhiro Yasuda,
  • Kenichi Koizumi,
  • Satoshi Yokojima,
  • Shinichiro Nakamura and
  • Kingo Uchida
Published 11 Jul 2019
Beilstein Arch. 2019, 201966. doi:10.3762/bxiv.2019.66.v1

Synthesis of diastereomeric pheromones: adjacent methyl-branched alcohols and ketones

  • VAN-DUNG LE,
  • Chi-Hien Dang,
  • Cong-Hao Nguyen,
  • Van-Su Dang and
  • Thanh-Danh Nguyen
Published 09 Jul 2019
Beilstein Arch. 2019, 201964. doi:10.3762/bxiv.2019.64.v1

1,3-Dipolar Cycloadditions of Isatin N,N′‑Cyclic Azomethine Imines with Alkynes for the synthesis of spiro[indoline-3,1'-pyrazolo[1,2-a]pyrazoles]

  • Yang Shi,
  • Gangqiang Wang,
  • Zhiyu Chen,
  • Minghu Wu,
  • Jian Wang,
  • Leslie Trigoura,
  • Haibing Guo,
  • Yalan Xing and
  • Shaofa Sun
Published 08 Jul 2019
Beilstein Arch. 2019, 201963. doi:10.3762/bxiv.2019.63.v1

Palladium-catalyzed Conia-ene Reaction of 1-alkynylindolin-3-ones: a strategy for the construction of Pyrrolo[1,2-a]indoles

  • Yong-Qin Tang,
  • Xing-Hai Fei,
  • Jian-Xiong An,
  • Fen-Fen Yang,
  • Dong-Zhu Duan,
  • Zuo-Xian Cao,
  • Xiao-Zhong Fu,
  • Yuan-Yong Yang,
  • Bin He and
  • Yong-Long Zhao
Published 04 Jul 2019
Beilstein Arch. 2019, 201959. doi:10.3762/bxiv.2019.59.v1

Azologization of a hetero-stilbene based c-RAF kinase inhibitor: Towards the design of photoswitchable sirtuin inhibitors

  • Christoph W. Grathwol,
  • Nathalie Wössner,
  • Sören Swyter,
  • Adam C. Smith,
  • Enrico Tapavicza,
  • Robert K. Hofstetter,
  • Anja Bodtke,
  • Manfred Jung and
  • Andreas Link
Published 01 Jul 2019
Beilstein Arch. 2019, 201953. doi:10.3762/bxiv.2019.53.v1

Sugar Derived Oxazolone Pseudotetrapeptide as γ-Turn Inducer and Anion-Selective Transporter

  • Sachin S. Burade,
  • Sushil V. Pawar,
  • Tanmoy Saha,
  • Navnath M Kumbhar,
  • Amol S. Kotmale,
  • Manzoor Ahmad,
  • Pinaki Talukdar and
  • Dilip D Dhavale
Published 27 Jun 2019
Beilstein Arch. 2019, 201949. doi:10.3762/bxiv.2019.49.v1

Ultrafast processes triggered by one- and two-photon excitation of a photochromic and luminescent hydrazone

  • Alessandro Iagatti,
  • Baihao Shao,
  • Alberto Credi,
  • Barbara Ventura,
  • Ivan Aprahamian and
  • Mariangela Di Donato
Published 27 Jun 2019
Beilstein Arch. 2019, 201948. doi:10.3762/bxiv.2019.48.v1

Excited State Dynamics for Visible Light Sensitization of Fast Photochromic Phenoxyl-Imidazolyl Radical Complex with Aryl Ketone

  • Yoichi Kobayashi,
  • Yukie Mamiya,
  • Katsuya Mutoh,
  • Hikaru Sotome,
  • Masafumi Koga,
  • Hiroshi Miyasaka and
  • Jiro Abe
Published 24 Jun 2019
Beilstein Arch. 2019, 201946. doi:10.3762/bxiv.2019.46.v1

Friedel-Crafts approach to the one-pot synthesis of methoxy substituted thioxanthylium salts

  • Kenta Tanaka,
  • Yuta Tanaka,
  • Mami Kishimoto,
  • Yujiro Hoshino and
  • Kiyoshi Honda
Published 21 Jun 2019
Beilstein Arch. 2019, 201941. doi:10.3762/bxiv.2019.41.v1

Synthesis of multi-substituted indene derivatives from aryl, vinyl, and alkyl/aryl carbinols

  • Mithun Chakraborty,
  • Gaddam Mahesh,
  • Omkar R. Nakel,
  • Gautamee Chavda,
  • Susarla Anusha and
  • Gangarajula Sudhakar
Published 07 Jun 2019
Beilstein Arch. 2019, 201939. doi:10.3762/bxiv.2019.39.v1

Archangelolide: Sesquiterpene lactone with immunobiological potential from Laserpitium archangelica

  • Silvie Rimpelová,
  • Michal Jurášek,
  • Lucie Peterková,
  • Jiří Bejček,
  • Vojtěch Spiwok,
  • Miloš Majdl,
  • Michal Jirásko,
  • Miloš Buděšínský,
  • Juraj Harmatha,
  • Eva Kmoníčková,
  • Pavel Drašar and
  • Tomáš Ruml
Published 04 Jun 2019
Beilstein Arch. 2019, 201938. doi:10.3762/bxiv.2019.38.v1

Synthesis of 1-azaspiro[4.4]nonan-1-oxyls via Intramolecular 1,3-Dipolar Cycloaddition

  • Yulia V. Khoroshunova,
  • Denis A. Morozov,
  • Andrey I. Taratayko,
  • Polina D. Gladkikh,
  • Yuri I. Glazachev and
  • Igor A. Kirilyuk
Published 03 Jun 2019
Beilstein Arch. 2019, 201937. doi:10.3762/bxiv.2019.37.v1

Installation of sulfonyl fluorides onto primary amides

  • Jing Liu,
  • Shi-Meng Wang and
  • Hua-Li Qin
Published 29 May 2019
Beilstein Arch. 2019, 201933. doi:10.3762/bxiv.2019.33.v1

Characterization of two new degradation products of atorvastatin-calcium formed upon treatment with strong acids

  • Jürgen Krauß,
  • Monika Klimt,
  • Markus Luber,
  • Peter Mayer and
  • Franz Bracher
Published 28 May 2019
Beilstein Arch. 2019, 201931. doi:10.3762/bxiv.2019.31.v1

Effect of Ring Size on Photoisomerization Properties of Stiff Stilbene macrocycles

  • Sandra Olsson,
  • Óscar Benito Pérez,
  • Magnus Blom and
  • Adolf Gogoll
Published 28 May 2019
Beilstein Arch. 2019, 201930. doi:10.3762/bxiv.2019.30.v1

Reaction of Arylmethyl Isocyanides/Arylmethyl-amines with Xanthate Esters: A Facile and Unexpected Synthesis of Carbamothioates

  • Narasimhamurthy Rajeev,
  • Toreshettahally R Swaroop,
  • Seegehalli M Anil,
  • Kupalli R Kiran,
  • Chandru Chandru,
  • Paris E Georghiou,
  • Ahmad I Alrawashdeh,
  • Shofiur Rahman,
  • Abdullah Alodhayb,
  • Kanchugarakoppal S Rangappa and
  • Maralinganadoddi P Sadashiva
Published 21 May 2019
Beilstein Arch. 2019, 201926. doi:10.3762/bxiv.2019.26.v1

Tautomerism as primary signalling mechanism in metal sensing: the case of amide group

  • Vera V. Deneva,
  • Georgi Dobrikov,
  • Aurelien Crochet,
  • Daniela Nedeltcheva,
  • Katharina M. Fromm and
  • Liudmil Antonov
Published 20 May 2019
Beilstein Arch. 2019, 201923. doi:10.3762/bxiv.2019.23.v1
Published 14 May 2019
Beilstein Arch. 2019, 201922. doi:10.3762/bxiv.2019.22.v1
Published 07 May 2019
Beilstein Arch. 2019, 201919. doi:10.3762/bxiv.2019.19.v1
Published 23 Apr 2019
Beilstein Arch. 2019, 201914. doi:10.3762/bxiv.2019.14.v1

Diazocine functionalized TATA Platforms

  • Roland Löw,
  • Talina Rusch,
  • Fynn Röhricht,
  • Olaf M. Magnussen and
  • Rainer Herges
Published 18 Apr 2019
Beilstein Arch. 2019, 201911. doi:10.3762/bxiv.2019.11.v1

Application of Chiral 2-Isoxazoline for the Synthesis of syn-1,3-Diol Analogues

  • Juanjuan Feng,
  • Tianyu Li,
  • Jiaxin Zhang and
  • Peng Jiao
Published 17 Apr 2019
Beilstein Arch. 2019, 201910. doi:10.3762/bxiv.2019.10.v1
Published 16 Apr 2019
Beilstein Arch. 2019, 20199. doi:10.3762/bxiv.2019.9.v1
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