The asymmetric Henry reaction as synthetic tool for production of drugs Linezolid and Rivaroxaban

  1. Martin Vrbický,
  2. Karel Macek,
  3. Jaroslav Pochobradský,
  4. Jan Svoboda,
  5. Miloš Sedlák and
  6. Pavel Drabina

Published 17 Jan 2022

Beilstein Arch. 2022, 20224. doi:10.3762/bxiv.2022.4.v1

Efficient continuous flow-synthesis of novel spiro-naphthalene-1,2'-[1,3,4]oxadiazol-4-ones

  1. Lange Yakubu Saleh,
  2. Bahadır Altıntaş,
  3. Layla Filiciotto,
  4. Yunus Zorlu,
  5. Rafael Luque and
  6. Cevher Altug

Published 17 Dec 2021

Beilstein Arch. 2021, 202189. doi:10.3762/bxiv.2021.89.v1

Anomeric 1,2,3-triazole-linked sialic acid derivatives show selective inhibition towards a bacterial neuraminidase over a trypanosome trans-sialidase

  1. Peterson de Andrade,
  2. Sanaz Ahmadipour and
  3. Robert A Field

Published 08 Nov 2021

Beilstein Arch. 2021, 202177. doi:10.3762/bxiv.2021.77.v1

First Total Synthesis of Hoshinoamides A  

  1. Haipin Zhou,
  2. Zihan Rui,
  3. Yiming Yang,
  4. Shengtao Xu,
  5. Yutian Shao and
  6. Long Liu

Published 15 Sep 2021

Beilstein Arch. 2021, 202164. doi:10.3762/bxiv.2021.64.v1

Ensemble-based virtual screening of Mycobacterium tuberculosis ClpC1 inhibitors

  1. Hafsa Tayyab,
  2. Nor F. W. Ridzwan and
  3. Saharuddin B. Mohamad

Published 06 Jul 2021

Beilstein Arch. 2021, 202150. doi:10.3762/bxiv.2021.50.v1

Phenylamino pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia

  1. Luiz Claudio Ferreira Pimentel,
  2. Lucas Villas Boas Hoelz,
  3. Henayle Fernandes Canzian,
  4. Frederico Silva Castelo Branco,
  5. Andressa Paula de Oliveira,
  6. Vinicius Rangel Campos,
  7. Floriano Paes Silva Júnior,
  8. Rafael Ferreira Dantas,
  9. Jackson Antônio Lamounier Camargos Resende,
  10. Anna Claudia Cunha,
  11. Nubia Boechat and
  12. Mônica Macedo Bastos

Published 09 Jun 2021

Beilstein Arch. 2021, 202144. doi:10.3762/bxiv.2021.44.v1

Design and synthesis of highly oxygenated furo[3,2-c]pyran-4-ones and furo[3,2-c]chromen-4-ones scaffold as potential anticancer and antimicrobial agent

  1. Suman Rani,
  2. Nisha Kamra,
  3. Sumit Thakral,
  4. Devinder Kumar,
  5. Ajeet Singh,
  6. Payare L Sangwan and
  7. Shashank K Singh

Published 17 May 2021

Beilstein Arch. 2021, 202137. doi:10.3762/bxiv.2021.37.v1

Novel coumarin compounds potentiate the effect of cisplatin on lung cancer cells by enhancing pro-apoptotic gene expressions, G2/M cell arrest, oxidative and antiangiogenic effects

  1. Adem Güner,
  2. Hakan Bektaş and
  3. Emre Menteşe

Published 14 Apr 2021

Beilstein Arch. 2021, 202133. doi:10.3762/bxiv.2021.33.v1

Me3Al mediated domino nucleophilic addition/intramolecular cyclisation of 2-(2-oxo-2-phenylethyl)benzonitriles with amines; A convenient approach for the synthesis of substituted 1-aminoisoquinolines

  1. Midhun Sai Krishna Adusumalli,
  2. Lakshmi Narayana Sharma Konidena,
  3. Hima Bindu Gandham,
  4. Krishnaiah Kumari,
  5. Krishna Reddy Valluru,
  6. Satya Kameswara Rao Nidasanametla,
  7. Venkateswara Rao Battula and
  8. Hari Krishna Namballa

Published 22 Mar 2021

Beilstein Arch. 2021, 202126. doi:10.3762/bxiv.2021.26.v1

Development of QSAR ensemble models for predicting the PAMPA Effective Permeability of new, non-peptidic leads with potential antiviral activity against the coronavirus SARS-CoV-2.

  1. Chrysoula Gousiadou,
  2. Philip Doganis and
  3. Haralambos Sarimveis

Published 15 Mar 2021

Beilstein Arch. 2021, 202122. doi:10.3762/bxiv.2021.22.v1

Enhanced cell target specificity and uptake of lipid nanoparticles using RNA aptamers and peptides

  1. Roslyn M. Ray,
  2. Anders Højgaard Hansen,
  3. Maria Taskova,
  4. Bernhard Jandl,
  5. Jonas Hansen,
  6. Citra Soemardy,
  7. Kevin V. Morris and
  8. Kira Astakhova

Published 26 Jan 2021

Beilstein Arch. 2021, 20217. doi:10.3762/bxiv.2021.7.v1

Borylated methyl cinnamates: Expedited synthesis, characterization, crystallographic analysis and biological activities in glycosidase inhibition and in cancer cells lines.

  1. William J Legge,
  2. Yuna Shimadate,
  3. Mahdi Ghorbani,
  4. Jennette Sakoff,
  5. Todd A Houston,
  6. Atsushi Kato,
  7. Paul Bernhardt and
  8. Michela I. Simone

Published 22 Jan 2021

Beilstein Arch. 2021, 20214. doi:10.3762/bxiv.2021.4.v1

β-Lactamase inhibition profile of new amidine substituted diazabicyclooctanes

  1. zafar iqbal,
  2. Yuanyu Gao,
  3. Dong Tang,
  4. Xueqin Ma,
  5. Jinbo Ji,
  6. Jian Sun,
  7. Jingwen Ji,
  8. Yuanbai Liu,
  9. Lijuan Zhai,
  10. Rui Jiang,
  11. Yangxiu Mu,
  12. Lili He,
  13. Haikang Yang and
  14. Zhixiang Yang

Published 21 Dec 2020

Beilstein Arch. 2020, 2020143. doi:10.3762/bxiv.2020.143.v1

DNA with zwitterionic and negatively charged phosphate modifications: formation of DNA triplexes, duplexes and cell permeability studies

  1. Yongdong Su,
  2. Maitsetseg Bayarjargal,
  3. Tracy K Hale and
  4. Vyacheslav V Filichev

Published 08 Dec 2020

Beilstein Arch. 2020, 2020138. doi:10.3762/bxiv.2020.138.v1

Synthesis and characterization of β-carboline fatty alcohol hybrids as potential biological active and antioxidant molecules

  1. Venkateshwarlu Kontham,
  2. Bhavya Ippakayala and
  3. Devarapaga Madhu

Published 30 Nov 2020

Beilstein Arch. 2020, 2020135. doi:10.3762/bxiv.2020.135.v1

Synthesis and physicochemical evaluation of fluorinated lipopeptide precursors of ligands for microbubble targeting

  1. Masayori HAGIMORI,
  2. Estefania E. MENDOZA-ORTEGA and
  3. Marie Pierre KRAFFT

Published 26 Nov 2020

Beilstein Arch. 2020, 2020133. doi:10.3762/bxiv.2020.133.v1

Synthesis of 1-Indolyl-3,5,8-Substituted γ-Carbolines: One Pot Metal-Solvent Free Protocol and Biological Evaluation

  1. Premansh Dudhe,
  2. Mena Asha Krishnan,
  3. Kratika Yadav,
  4. Diptendu Roy,
  5. Krishnan Venkatasubbaiah,
  6. Biswarup Pathak and
  7. Venkatesh Chelvam

Published 19 Nov 2020

Beilstein Arch. 2020, 2020131. doi:10.3762/bxiv.2020.131.v1

In silico approach: Anthocyanin derivatives as potential inhibitors of the COVID-19 main protease

  1. Muhammad Ikhlas Abdjan,
  2. Khusna Arif Rakhman,
  3. Sri Handayani,
  4. Chairil Anjasmara Robo Putra and
  5. Imam Siswanto

Published 15 Sep 2020

Beilstein Arch. 2020, 2020106. doi:10.3762/bxiv.2020.106.v1

Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity

  1. Yuvixza Lizarme-Salas,
  2. Alexandra Daryl Ariawan,
  3. Ranjala Ratnayake,
  4. Hendrik Luesch,
  5. Angela Finch and
  6. Luke Hunter

Published 12 Aug 2020

Beilstein Arch. 2020, 202093. doi:10.3762/bxiv.2020.93.v1

Convenient Synthesis and Biological Evaluation of Bis(indolyl)methane Alkaloid and Bis(aryl)alkanes Derivatives with Anti-cancer Properties  

  1. Liang Qi,
  2. Linxia Xiao and
  3. Rui Lin

Published 08 May 2020

Beilstein Arch. 2020, 202060. doi:10.3762/bxiv.2020.60.v1

Facile Synthesis of 7-Alkyl-1,2,3,4-tetrahydro-[1,8]-naphthyridines as Arginine Mimetics Using a Horner–Wadsworth–Emmons Based Approach

  1. Rhys A Lippa,
  2. John A Murphy and
  3. Tim Barrett

Published 27 Apr 2020

Beilstein Arch. 2020, 202055. doi:10.3762/bxiv.2020.55.v1

A study on the synthesis of β-amino acids: the first synthesis of a bicyclic hemiaminal (3,3-dimethyl-1-(2,4,5-trifluorophenyl) tetrahydro-3H,5H-oxazolo[3,4-c] [1,3] oxazin-5-one)

  1. Ozlem Gundogdu,
  2. Ertan Sahin and
  3. Yunus Kara

Published 21 Apr 2020

Beilstein Arch. 2020, 202053. doi:10.3762/bxiv.2020.53.v1

Design, synthesis and biological evaluation of novel 5-bromo derivatives of indole phytoalexins

  1. Mariana Budovská,
  2. Ivana Selešová,
  3. Viera Tischlerová,
  4. Radka Michalková and
  5. Ján Mojžiš

Published 05 Mar 2020

Beilstein Arch. 2020, 202023. doi:10.3762/bxiv.2020.23.v1

Reaction of indoles with aromatic fluoromethyl ketones: An efficient synthesis of trifluoromethyl-indolyl-phenylethanols using K2CO3/nBu4PBr in water

  1. Thanigaimalai Pillaiyar,
  2. Masoud Sedaghati and
  3. Gregor Schnakenburg

Published 12 Feb 2020

Beilstein Arch. 2020, 202017. doi:10.3762/bxiv.2020.17.v1

Smart DNA biosensor for in vitro detection of androgen receptor mRNA

  1. Ekaterina Alexandrovna Bryushkova,
  2. Erik Rafikovich Gandalipov and
  3. Julia Victorovna Nuzhina

Published 23 Jan 2020

Beilstein Arch. 2020, 202013. doi:10.3762/bxiv.2020.13.v1

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