Facile and Diastereoselective Arylation of the Privileged 1,4-Dihydroisoquinolin-3(2H)-one Scaffold

  1. Dmitry Dar'in,
  2. Grigory Kantin,
  3. Alexander Bunev and
  4. Mikhail Krasavin

Published 20 Jun 2022

Beilstein Arch. 2022, 202250. doi:10.3762/bxiv.2022.50.v1

Novel one-pot synthesis of 2-thio-substituted-3-H-phenothiazin-3-ones driven by oxidation with sodium periodate

  1. Herman H. Odens Jr.,
  2. Jae Y. You,
  3. Alexandria D. Gallimore,
  4. Preston H. Palm,
  5. Cameron W. Davis,
  6. Josue M. Bahena,
  7. Jeffrey S. Moser,
  8. Mackenzie E. Smith and
  9. Herman H. Odens

Published 13 May 2022

Beilstein Arch. 2022, 202236. doi:10.3762/bxiv.2022.36.v1

New triazole triterpene derivative exhibits anti-RSV activity synthesis biological evaluation and molecular modeling

  1. Elenilson Figueiredo da Silva,
  2. Krist Helen Antunes Fernandes,
  3. Denise Diedrich,
  4. Jessica Gotardi,
  5. Marcia Silvana Freire Franco,
  6. Carlos Henrique Tomich de P da Silva,
  7. Ana Paula Duarte de Souza and
  8. Simone Cristina Baggio Gnoatto

Published 29 Apr 2022

Beilstein Arch. 2022, 202231. doi:10.3762/bxiv.2022.31.v1

Scope of Tetrazolo[1,5-a]quinoxalines in CuAAC reactions for the Synthesis of  Triazoloquinoxalines,  Imidazoloquinoxalines, and Rhenium-complexes thereof

  1. Laura Holzhauer,
  2. Chloé Liagre,
  3. Olaf Fuhr,
  4. Nicole Jung and
  5. Stefan Bräse

Published 28 Feb 2022

Beilstein Arch. 2022, 202210. doi:10.3762/bxiv.2022.10.v1

The asymmetric Henry reaction as synthetic tool for production of drugs Linezolid and Rivaroxaban

  1. Martin Vrbický,
  2. Karel Macek,
  3. Jaroslav Pochobradský,
  4. Jan Svoboda,
  5. Miloš Sedlák and
  6. Pavel Drabina

Published 17 Jan 2022

Beilstein Arch. 2022, 20224. doi:10.3762/bxiv.2022.4.v1

Anomeric 1,2,3-triazole-linked sialic acid derivatives show selective inhibition towards a bacterial neuraminidase over a trypanosome trans-sialidase

  1. Peterson de Andrade,
  2. Sanaz Ahmadipour and
  3. Robert A Field

Published 08 Nov 2021

Beilstein Arch. 2021, 202177. doi:10.3762/bxiv.2021.77.v1

First Total Synthesis of Hoshinoamides A  

  1. Haipin Zhou,
  2. Zihan Rui,
  3. Yiming Yang,
  4. Shengtao Xu,
  5. Yutian Shao and
  6. Long Liu

Published 15 Sep 2021

Beilstein Arch. 2021, 202164. doi:10.3762/bxiv.2021.64.v1

Host-guest interaction and properties of cucurbit[8]uril with chloramphenicol

  1. Lin Zhang,
  2. Jun Zheng,
  3. Guangyan Luo,
  4. Xiaoyue Li,
  5. Yunqian Zhang,
  6. Zhu Tao and
  7. Qianjun Zhang

Published 30 Aug 2021

Beilstein Arch. 2021, 202162. doi:10.3762/bxiv.2021.62.v1

Ensemble-based virtual screening of Mycobacterium tuberculosis ClpC1 inhibitors

  1. Hafsa Tayyab,
  2. Nor F. W. Ridzwan and
  3. Saharuddin B. Mohamad

Published 06 Jul 2021

Beilstein Arch. 2021, 202150. doi:10.3762/bxiv.2021.50.v1

Phenylamino pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia

  1. Luiz Claudio Ferreira Pimentel,
  2. Lucas Villas Boas Hoelz,
  3. Henayle Fernandes Canzian,
  4. Frederico Silva Castelo Branco,
  5. Andressa Paula de Oliveira,
  6. Vinicius Rangel Campos,
  7. Floriano Paes Silva Júnior,
  8. Rafael Ferreira Dantas,
  9. Jackson Antônio Lamounier Camargos Resende,
  10. Anna Claudia Cunha,
  11. Nubia Boechat and
  12. Mônica Macedo Bastos

Published 09 Jun 2021

Beilstein Arch. 2021, 202144. doi:10.3762/bxiv.2021.44.v1

Design and synthesis of highly oxygenated furo[3,2-c]pyran-4-ones and furo[3,2-c]chromen-4-ones scaffold as potential anticancer and antimicrobial agent

  1. Suman Rani,
  2. Nisha Kamra,
  3. Sumit Thakral,
  4. Devinder Kumar,
  5. Ajeet Singh,
  6. Payare L Sangwan and
  7. Shashank K Singh

Published 17 May 2021

Beilstein Arch. 2021, 202137. doi:10.3762/bxiv.2021.37.v1

Novel coumarin compounds potentiate the effect of cisplatin on lung cancer cells by enhancing pro-apoptotic gene expressions, G2/M cell arrest, oxidative and antiangiogenic effects

  1. Adem Güner,
  2. Hakan Bektaş and
  3. Emre Menteşe

Published 14 Apr 2021

Beilstein Arch. 2021, 202133. doi:10.3762/bxiv.2021.33.v1

Development of QSAR ensemble models for predicting the PAMPA Effective Permeability of new, non-peptidic leads with potential antiviral activity against the coronavirus SARS-CoV-2.

  1. Chrysoula Gousiadou,
  2. Philip Doganis and
  3. Haralambos Sarimveis

Published 15 Mar 2021

Beilstein Arch. 2021, 202122. doi:10.3762/bxiv.2021.22.v1

Enhanced cell target specificity and uptake of lipid nanoparticles using RNA aptamers and peptides

  1. Roslyn M. Ray,
  2. Anders Højgaard Hansen,
  3. Maria Taskova,
  4. Bernhard Jandl,
  5. Jonas Hansen,
  6. Citra Soemardy,
  7. Kevin V. Morris and
  8. Kira Astakhova

Published 26 Jan 2021

Beilstein Arch. 2021, 20217. doi:10.3762/bxiv.2021.7.v1

Borylated methyl cinnamates: Expedited synthesis, characterization, crystallographic analysis and biological activities in glycosidase inhibition and in cancer cells lines.

  1. William J Legge,
  2. Yuna Shimadate,
  3. Mahdi Ghorbani,
  4. Jennette Sakoff,
  5. Todd A Houston,
  6. Atsushi Kato,
  7. Paul Bernhardt and
  8. Michela I. Simone

Published 22 Jan 2021

Beilstein Arch. 2021, 20214. doi:10.3762/bxiv.2021.4.v1

β-Lactamase inhibition profile of new amidine substituted diazabicyclooctanes

  1. zafar iqbal,
  2. Yuanyu Gao,
  3. Dong Tang,
  4. Xueqin Ma,
  5. Jinbo Ji,
  6. Jian Sun,
  7. Jingwen Ji,
  8. Yuanbai Liu,
  9. Lijuan Zhai,
  10. Rui Jiang,
  11. Yangxiu Mu,
  12. Lili He,
  13. Haikang Yang and
  14. Zhixiang Yang

Published 21 Dec 2020

Beilstein Arch. 2020, 2020143. doi:10.3762/bxiv.2020.143.v1

DNA with zwitterionic and negatively charged phosphate modifications: formation of DNA triplexes, duplexes and cell permeability studies

  1. Yongdong Su,
  2. Maitsetseg Bayarjargal,
  3. Tracy K Hale and
  4. Vyacheslav V Filichev

Published 08 Dec 2020

Beilstein Arch. 2020, 2020138. doi:10.3762/bxiv.2020.138.v1

Synthesis and characterization of β-carboline fatty alcohol hybrids as potential biological active and antioxidant molecules

  1. Venkateshwarlu Kontham,
  2. Bhavya Ippakayala and
  3. Devarapaga Madhu

Published 30 Nov 2020

Beilstein Arch. 2020, 2020135. doi:10.3762/bxiv.2020.135.v1

Synthesis and physicochemical evaluation of fluorinated lipopeptide precursors of ligands for microbubble targeting

  1. Masayori HAGIMORI,
  2. Estefania E. MENDOZA-ORTEGA and
  3. Marie Pierre KRAFFT

Published 26 Nov 2020

Beilstein Arch. 2020, 2020133. doi:10.3762/bxiv.2020.133.v1

Synthesis of 1-Indolyl-3,5,8-Substituted γ-Carbolines: One Pot Metal-Solvent Free Protocol and Biological Evaluation

  1. Premansh Dudhe,
  2. Mena Asha Krishnan,
  3. Kratika Yadav,
  4. Diptendu Roy,
  5. Krishnan Venkatasubbaiah,
  6. Biswarup Pathak and
  7. Venkatesh Chelvam

Published 19 Nov 2020

Beilstein Arch. 2020, 2020131. doi:10.3762/bxiv.2020.131.v1

In silico approach: Anthocyanin derivatives as potential inhibitors of the COVID-19 main protease

  1. Muhammad Ikhlas Abdjan,
  2. Khusna Arif Rakhman,
  3. Sri Handayani,
  4. Chairil Anjasmara Robo Putra and
  5. Imam Siswanto

Published 15 Sep 2020

Beilstein Arch. 2020, 2020106. doi:10.3762/bxiv.2020.106.v1

Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity

  1. Yuvixza Lizarme-Salas,
  2. Alexandra Daryl Ariawan,
  3. Ranjala Ratnayake,
  4. Hendrik Luesch,
  5. Angela Finch and
  6. Luke Hunter

Published 12 Aug 2020

Beilstein Arch. 2020, 202093. doi:10.3762/bxiv.2020.93.v1

Convenient Synthesis and Biological Evaluation of Bis(indolyl)methane Alkaloid and Bis(aryl)alkanes Derivatives with Anti-cancer Properties  

  1. Liang Qi,
  2. Linxia Xiao and
  3. Rui Lin

Published 08 May 2020

Beilstein Arch. 2020, 202060. doi:10.3762/bxiv.2020.60.v1

Facile Synthesis of 7-Alkyl-1,2,3,4-tetrahydro-[1,8]-naphthyridines as Arginine Mimetics Using a Horner–Wadsworth–Emmons Based Approach

  1. Rhys A Lippa,
  2. John A Murphy and
  3. Tim Barrett

Published 27 Apr 2020

Beilstein Arch. 2020, 202055. doi:10.3762/bxiv.2020.55.v1

A study on the synthesis of β-amino acids: the first synthesis of a bicyclic hemiaminal (3,3-dimethyl-1-(2,4,5-trifluorophenyl) tetrahydro-3H,5H-oxazolo[3,4-c] [1,3] oxazin-5-one)

  1. Ozlem Gundogdu,
  2. Ertan Sahin and
  3. Yunus Kara

Published 21 Apr 2020

Beilstein Arch. 2020, 202053. doi:10.3762/bxiv.2020.53.v1

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