An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent

  1. Nicky J Willis,
  2. Elliott D Bayle,
  3. George Papageorgiou,
  4. David Steadman,
  5. Benjamin N Aktinson,
  6. William Mahy and
  7. Paul V Fish

Published 16 Jul 2019

Beilstein Arch. 2019, 201970. doi:10.3762/bxiv.2019.70.v1

A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light

  1. Xavier Gómez-Santacana,
  2. Sabrina M. de Munnik,
  3. Tamara A. M. Mocking,
  4. Niels J. Hauwert,
  5. Shanliang Sun,
  6. Prashanna Vijayachandran,
  7. Iwan J. P. de Esch,
  8. Henry F. Vischer,
  9. Maikel Wijtmans and
  10. Rob Leurs

Published 15 Jul 2019

Beilstein Arch. 2019, 201969. doi:10.3762/bxiv.2019.69.v1

Azologization of a hetero-stilbene based c-RAF kinase inhibitor: Towards the design of photoswitchable sirtuin inhibitors

  1. Christoph W. Grathwol,
  2. Nathalie Wössner,
  3. Sören Swyter,
  4. Adam C. Smith,
  5. Enrico Tapavicza,
  6. Robert K. Hofstetter,
  7. Anja Bodtke,
  8. Manfred Jung and
  9. Andreas Link

Published 01 Jul 2019

Beilstein Arch. 2019, 201953. doi:10.3762/bxiv.2019.53.v1

Characterization of two new degradation products of atorvastatin-calcium formed upon treatment with strong acids

  1. Jürgen Krauß,
  2. Monika Klimt,
  3. Markus Luber,
  4. Peter Mayer and
  5. Franz Bracher

Published 28 May 2019

Beilstein Arch. 2019, 201931. doi:10.3762/bxiv.2019.31.v1

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