1,3-Dipolar Cycloadditions of Isatin N,N′‑Cyclic Azomethine Imines with Alkynes for the synthesis of spiro[indoline-3,1'-pyrazolo[1,2-a]pyrazoles]

  1. Yang Shi,
  2. Gangqiang Wang,
  3. Zhiyu Chen,
  4. Minghu Wu,
  5. Jian Wang,
  6. Leslie Trigoura,
  7. Haibing Guo ,
  8. Yalan Xing ORCID Logo and
  9. Shaofa Sun

Submitting author affiliation: Hubei University of Science and Technology, Xianning, China

Beilstein Arch. 2019, 201963. doi:10.3762/bxiv.2019.63.v1

Published 08 Jul 2019

  • Preprint

Abstract

CuCO3 catalyzed 1, 3-dipolar cycloaddition of isatin N,N′‑cyclic azomethine imine has been developed.  Biologically active heterocyclic spiro[indoline-3,1'-pyrazolo[1,2-a]pyrazoles] were prepared as single regioisomers in good yields and functional group compatibility.

Keywords: cycloaddition isatin N,N′‑Cyclic Azomethine Imines heterocycles 1,3-Dipolar

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When a peer-reviewed version of this preprint is available in the Beilstein Journals, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Shi, Y.; Wang, G.; Chen, Z.; Wu, M.; Wang, J.; Trigoura, L.; Guo, H.; Xing, Y.; Sun, S. Beilstein Arch. 2019, 201963. doi:10.3762/bxiv.2019.63.v1

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