A Novel Sustainable Method to Prepare Glutaric Acid from Glucose

  1. Lei HaoORCID Logo,
  2. Chao Jie Li,
  3. Lian Bo Zhao,
  4. Xi Xian Xie and
  5. Kui Lu

Submitting author affiliation: Tianjin University of Science and Technology, Tianjin, China

Beilstein Arch. 2020, 202062. https://doi.org/10.3762/bxiv.2020.62.v1

Published 19 May 2020

  • Preprint


This paper proposes a sustainable method to prepare glutaric acid from glucose via an α-keto glutaric acid derived from glucose by fermentation using Corynebacterium glutamicum GKGA. Glutaric acid was prepared from α-keto glutaric acid via the hydrogenation of a 1,3-dithiolane diamide intermediate as the key step. The combination of biotransformation and chemical transformation of glutaric acid provided an efficient and environment-friendly method for the sustainable synthesis of glutaric acid

Keywords: Glutamic acid;α-Keto glutaric acid; Glucose; Fermertation; Chemical transformation

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When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Hao, L.; Li, C. J.; Zhao, L. B.; Xie, X. X.; Lu, K. Beilstein Arch. 2020, 202062. doi:10.3762/bxiv.2020.62.v1

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