A Novel Sustainable Method to Prepare Glutaric Acid from Glucose

Submitting author affiliation:
Tianjin University of Science and Technology, Tianjin, China

Beilstein Arch. 2020, 202062. https://doi.org/10.3762/bxiv.2020.62.v1

Published 19 May 2020

This preprint has not been peer-reviewed. When a peer-reviewed version is available, this information will be updated.


This paper proposes a sustainable method to prepare glutaric acid from glucose via an α-keto glutaric acid derived from glucose by fermentation using Corynebacterium glutamicum GKGA. Glutaric acid was prepared from α-keto glutaric acid via the hydrogenation of a 1,3-dithiolane diamide intermediate as the key step. The combination of biotransformation and chemical transformation of glutaric acid provided an efficient and environment-friendly method for the sustainable synthesis of glutaric acid

Keywords: Glutamic acid;α-Keto glutaric acid; Glucose; Fermertation; Chemical transformation

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When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Hao, L.; Li, C. J.; Zhao, L. B.; Xie, X. X.; Lu, K. Beilstein Arch. 2020, 202062. doi:10.3762/bxiv.2020.62.v1

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