Supramolecular Assemblies of Donor-Acceptor Stenhouse Adduct Amphiphiles as Macroscopic Soft Scaffolds

Submitting author affiliation:
The Hong Kong Polytechnic University, Hong Kong, Hong Kong

Beilstein Arch. 2024, 202424.

Published 17 Apr 2024

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Designing photo-harvesting and photoresponsive supramolecular systems in aqueous media, the fabrication of photoswitch as an amphiphilic structure enables non-invasive functional response by photoirradiation. Although most of aqueous supramolecular assemblies across multiple length-scale were driven by high-energy and bio-damaging UV-light, previously we reported donor-acceptor Stenhouse adduct (DASA) amphiphile controlled by while-light. Herein, we present a series of DASA amphiphiles with minor structural modifications on the chain length of alkyl-linker, which connect DASA motif with hydrophilic part. The excellent photoswitchabilities in organic media and photoresponsiveness in aqueous media, driven by visible-light, are revealed with UV-vis absorption spectroscopy. The supramolecular structures are confirmed by electronic microscopies across multiple length-scale, while the supramolecular packing structures at macroscopic length-scale are revealed with X-ray diffraction. Driven by visible-light irradiation, the large geometrical transformations of DASA amphiphiles enable supramolecular transformation at microscopic length-scale, and subsequently disassemble the macroscopic soft scaffolds of DASA amphiphiles. The results indicate the feasibility in developing visible-light controlled macroscopic scaffolds for offering opportunity in fabricating biomedical materials with visible-light controlled microenvironment and future soft robotic systems.

Keywords: Donor-Acceptor Stenhouse Adduct; Supramolecular Transformation; Photoresponsive Molecular Amphiphile; Visible-Light

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When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Hung, K.-L.; Cheung, L.-H.; Ren, Y.; Chau, M.-H.; Lam, Y.-Y.; Kajitani, T.; Leung, F. K.-C. Beilstein Arch. 2024, 202424. doi:10.3762/bxiv.2024.24.v1

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