Beilstein Arch. 2023, 202325. https://doi.org/10.3762/bxiv.2023.25.v1
Published 13 Jun 2023
Two bench stable palladium(II) complexes [k2-(PyCH=N(CHPh2)PdCl2)] (1) and [k3-(PyCH=N(CH(Ph2)(C6H4))PdCl)] (2) supported by iminopyridine ligands (PyCH=NR) [R = CHPh2, (L1) and R = CPh3, (L2)] were synthesized and utilized as the competent catalysts in the formation of C-C coupling products for Suzuki-Miyaura and Heck-Mizoroki reactions. The palladium complex 1 was obtained by the k2 coordination of the ligand L1 to the palladium precursor whereas complex 2 was achieved by ortho-metallation of one of the phenyl groups present in ligand L2 with the Pd metal under reaction conditions making the ligand k3-ligation to the metal. Complex 2 exhibited excellent catalytic efficiency at very low catalyst loading (0.5 mol%). The new C-C bond formations of the desired products were obtained in high yield at mild reaction conditions. Wide varieties of substrate scopes were explored for the C-C bond cross-coupling reactions.
Keywords: Palladium Catalysis • Suzuki-Miyaura Coupling • Heck-Mizoroki Coupling and one-pot synthesis.
|Format: DOCX||Size: 4.6 MB||Download|
When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:
Kisan, D. A.; Kumar, G. S.; Sunar, S. L.; Sau, A.; Panda, T. K. Beilstein Arch. 2023, 202325. doi:10.3762/bxiv.2023.25.v1
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.
© 2023 Kisan et al.; licensee Beilstein-Institut.
This is an open access work licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-archives.org/xiv/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this work could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.