Design and Synthesis of Planar Chiral Bisphosphine Ligands Based on Diphenyl [2.2]-Paracyclophane

  1. Shaoying Huang,
  2. Jiaping Jin and
  3. Xufeng LinORCID Logo

Submitting author affiliation: Zhejaing University, Hangzhou, China

Beilstein Arch. 2021, 202183. https://doi.org/10.3762/bxiv.2021.83.v1

Published 30 Nov 2021

  • Preprint

Abstract

Planar chiral bisphosphine ligands based on diphenyl [2.2]paracyclophane (PhPhanePHOS)  were successfully synthesized in a practical manner in four steps from commercially available 4,12-bisbromo-[2.2]paracyclophane as a new family of bisphosphine ligands. The novel PhPhanePHOS ligands provide high catalytic activity in Pd-catalyzed asymmetric allylalkylation reactions in preliminary experiments.

Keywords: asymmetric catalysis, planar chiral ligand, bisphosphine ligand, paracyclophane, asymmetric reactions

Supporting Information

Format: DOCX Size: 2.9 MB   Download

How to Cite

When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Huang, S.; Jin, J.; Lin, X. Beilstein Arch. 2021, 202183. doi:10.3762/bxiv.2021.83.v1

Download Citation
Download RIS (Reference Manager) Download BIB (BIBTEX)

© 2021 Huang et al.; licensee Beilstein-Institut.
This is an open access work licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-archives.org/xiv/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this work could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.

Other Beilstein-Institut Open Science Activities

Logo
Logo
Logo
Symposia