A convergent strategy is reported for the construction of nitrogen-containing heterocycles from common substrates: 1,4-diketones and primary amines. Indeed, by just varying substrates, substituents or heating mode it is possible to selectively synthesize indole, indolone (1,5,6,7-tetradihydroindol-4-one) or cinnoline (5,6,7,8-tetrahydrocinnoline) derivatives in moderate to excellent yields.
Keywords: N-heterocycle; 1,4-diketone; indole; indolone; cinnoline
|Format: PDF||Size: 5.2 MB||Download|
When a peer-reviewed version of this preprint is available in the Beilstein Journals, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:
El-Marrouki, D.; Touchet, S.; Abdelli, A.; M'Rabet, H.; Lotfi Efrit, M.; Gros, P. C. Beilstein Arch. 2020, 202056. doi:10.3762/bxiv.2020.56.v1
|Download RIS (Reference Manager)||Download BIB (BIBTEX)|