A robust transition metal-free strategy is presented to access novel β-carboline tethered benzothiophenone derivatives from 1(3)-formyl-β-carbolines using elemental sulphur activated by Et3N/DMSO. This expeditious catalyst-free reaction proceeds through the formation of β-carboline based 2-nitrochalcones followed by incorporation of sulphur to generate the multifunctional β-carboline linked benzothiophenones in good to excellent yields. The synthetic strategy can also be extended towards the synthesis of β-carboline linked benzothiophenes. Moreover, the products as afforded thereof emerged as promising fluorophores and displayed excellent light-emitting properties with quantum yield (ΦF) upto 47%.
Keywords: β-Carboline; Metal-free; Sulphur insertion; Benzothiophene; Photophysical properties
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Singh, D.; Kumar, V.; Singh, V. Beilstein Arch. 2020, 202052. doi:10.3762/bxiv.2020.52.v1
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