Microwave-assisted efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-2,3-dihydro-1,3,5-triazine-2,4-diamines

  1. Moustafa MoustafaORCID Logo,
  2. Ramadan Mekheimer,
  3. Saleh Al-Mousawi,
  4. Mohamed Abd-Elmonem,
  5. Hesham El-Zorba,
  6. Afaf Abdel Hameed,
  7. Tahany Mohamed and
  8. Kamal Usef SadekORCID Logo

Submitting author affiliation: Minia University, Minia, Egypt

Beilstein Arch. 2020, 202051. doi:10.3762/bxiv.2020.51.v1

Published 16 Apr 2020

  • Preprint

Abstract

An efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of obtained products.

 

Keywords: N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamines; Microwave irradiation; one-pot synthesis; X-ray crystallography

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When a peer-reviewed version of this preprint is available in the Beilstein Journals, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Moustafa, M.; Mekheimer, R.; Al-Mousawi, S.; Abd-Elmonem, M.; El-Zorba, H.; Abdel Hameed, A.; Mohamed, T.; Sadek, K. U. Beilstein Arch. 2020, 202051. doi:10.3762/bxiv.2020.51.v1

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