An efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of obtained products.
Keywords: N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamines; Microwave irradiation; one-pot synthesis; X-ray crystallography
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Moustafa, M.; Mekheimer, R.; Al-Mousawi, S.; Abd-Elmonem, M.; El-Zorba, H.; Abdel Hameed, A.; Mohamed, T.; Sadek, K. U. Beilstein Arch. 2020, 202051. doi:10.3762/bxiv.2020.51.v1
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