Abstract

Biogenic synthesis of silver nanoparticles (SS-Ag NPs) using the extract of Saccharum spontaneum (SS) via green chemistry route was investigated for their in-vitro cytotoxicity on osteoblast-like cells and bactericidal effect. Synthesized SS-Ag NPs were analyzed using TEM, FTIR, XRD and UV Vis spectroscopy techniques. The biomolecules present in S. spontaneum were responsible for the reduction and capping of silver nanoparticles. A heterogenous mixture of SS-Ag NPs which consists of triangle, hexagonal, spherical and rod-like structures was obtained. Furthermore, the synthesized SS-Ag NPs were tested for in a broad spectrum of antibacterial activity against E. coli, S. aureus, K. pneumonia and P. aeruginosa and it showed significant inhibitory effect. For the first time, the enhancement in the proliferation rate of MG63 cells with SS-Ag NPs is reported.

Keywords: Silver nanoparticles, Biogenic synthesis, Antibacterial, In-vitro studies.

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Balu, S.; Andra, S.; Kannan, S.; S, M. V.; Muthalagu, M. Beilstein Arch. 2019, 201958. doi:10.3762/bxiv.2019.58.v1

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