Total synthesis of 2'-O-methyl-β-L-arabinosyluridine and reassignment the nucleoside from Penicillium sp. as 2'-O-methyl-β-L-uridine

Submitting author affiliation:
Jiangxi Science & Technology Normal University, Nanchang, China

Beilstein Arch. 2019, 2019128. https://doi.org/10.3762/bxiv.2019.128.v1

Published 23 Oct 2019

Preprint
This preprint has not been peer-reviewed. When a peer-reviewed version is available, this information will be updated.

Abstract

In order to validate the structure of a rarely reported naturally occurring nucleoside isolated from the broth of Penicillium sp. (NO. 64), practical syntheses of 2'-O-methyl-β-L-arabinosyluridine, 2'-O-methyl-α-L-arabinosyluridine, and 2'-O-methyl-β-L-uridine were accomplished. Comparing their nuclear magnetic resonance (NMR) spectra and physical data, its structure was reassigned as 2'-O-methyl-β-L-uridine instead of former reported 2'-O-methyl-β-L-arabinosyluridine.

Keywords:

Supporting Information

Format: PDF Size: 1.1 MB   Download

How to Cite

When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

shen, C.; Ding, H.; Tao, X.; Yang, R.; Bai, J.; Cao, B.; Peng, Y.; Xiao, Q. Beilstein Arch. 2019, 2019128. doi:10.3762/bxiv.2019.128.v1

Download citation
Download RIS (Reference Manager) Download BIB (BIBTEX)

© 2019 shen et al.; licensee Beilstein-Institut.
This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited.
The license is subject to the Beilstein Archives terms and conditions: (https://www.beilstein-archives.org/xiv/terms)

OTHER BEILSTEIN-INSTITUT OPEN SCIENCE ACTIVITIES