Small protein sequences can induce cellular uptake of complex nanohybrids

  1. Jan-Philip MerklORCID Logo,
  2. Malak Safi,
  3. Christian Schmidtke,
  4. Fadi Aldeek,
  5. Johannes Ostermann,
  6. Tatiana Domitrovic,
  7. Sebastian Gärtner,
  8. John E. Johnson,
  9. Horst Weller and
  10. Hedi Mattoussi

Submitting author affiliation: University of Hamburg, Hamburg, Germany

Beilstein Arch. 2019, 2019111.

Published 27 Sep 2019

  • Preprint


In this letter, we highlight that a low fraction of functional fusion proteins can significantly change the interaction of complex nanohybrids with cells and induce cellular uptake.

Keywords: Nanoparticle hybrids, polymer encapsulation, self-assembly, cellular uptake, bioconjugation

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When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Merkl, J.-P.; Safi, M.; Schmidtke, C.; Aldeek, F.; Ostermann, J.; Domitrovic, T.; Gärtner, S.; Johnson, J. E.; Weller, H.; Mattoussi, H. Beilstein Arch. 2019, 2019111. doi:10.3762/bxiv.2019.111.v1

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