Beilstein Arch. 2019, 201910. https://doi.org/10.3762/bxiv.2019.10.v1
Published 17 Apr 2019
Asymmetric cycloaddition of TIPS nitronate catalyzed by “Cu(II)-bisoxazoline” gave the 2-isoxazoline product in 85% yield, which was converted into t-butyl (3S,5R)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate in 11 steps via a β-hydroxy ketone.
Keywords: cycloaddition; silyl nitronate; isoxazoline; β-hydroxy ketone; 1,3-diol
|Format: PDF||Size: 6.6 MB||Download|
When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:
Feng, J.; Li, T.; Zhang, J.; Jiao, P. Beilstein Arch. 2019, 201910. doi:10.3762/bxiv.2019.10.v1
|Download RIS (Reference Manager)||Download BIB (BIBTEX)|
© 2019 Feng et al.; licensee Beilstein-Institut.
This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited.
The license is subject to the Beilstein Archives terms and conditions: (https://www.beilstein-archives.org/xiv/terms)