Rongalite addition to dienones: diastereoselectivity in cyclic sulfone synthesis; stereochemical rationalization and prospects as a general conjugate nucleophile

  • Melina Goga,
  • Hao Zong,
  • James Franco,
  • Jazmine Prana,
  • Rudolph Michel,
  • Antonia Muro,
  • Elana Rubin,
  • Janet Brenya,
  • Henk Eshuis and
  • Magnus W. P. Bebbington

Beilstein J. Org. Chem. 2026, 22, 742–752, doi:10.3762/bjoc.22.56

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Published 13 May 2026

Synthesis of heterocycles based on azomethine ylides from α-amino acids (or amines) and carbonyl compounds

  • Ekaterina V. Berezhnaya,
  • Alexander I. Ponyaev,
  • Vitali M. Boitsov and
  • Alexander V. Stepakov

Beilstein J. Org. Chem. 2026, 22, 705–741, doi:10.3762/bjoc.22.55

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Review
Published 13 May 2026

Anti-invasive and cytotoxic evaluation of a (+)-pinoresinol-based semisynthetic library against glioblastoma

  • Chen Zhang,
  • Kah Yean Lum,
  • Jonathan M. White,
  • Paul I. Forster,
  • Nicholas Booth,
  • Sunita A. Ramesh and
  • Rohan A. Davis

Beilstein J. Org. Chem. 2026, 22, 691–704, doi:10.3762/bjoc.22.54

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Published 11 May 2026

Synthesis of depressin, cryptomeridiol and 4-epi-cryptomeridiol enabled by a terpenoid chiral pool-producing platform

  • Yao Kong,
  • Tao Wang,
  • Chen Wang,
  • Pengcheng Zhang,
  • Yuanning Liu,
  • Kaibiao Wang,
  • Fen Liu,
  • Hongli Jia and
  • Zhengren Xu

Beilstein J. Org. Chem. 2026, 22, 683–690, doi:10.3762/bjoc.22.53

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Published 05 May 2026

Harnessing light energy with molecules

  • Grace G. D. Han,
  • Mogens Brøndsted Nielsen and
  • Hermann A. Wegner

Beilstein J. Org. Chem. 2026, 22, 680–682, doi:10.3762/bjoc.22.52

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Editorial
Published 04 May 2026

Using generative AI to transform peptide hits into small molecule leads

  • Joshua Mills and
  • Yu Heng Lau

Beilstein J. Org. Chem. 2026, 22, 672–679, doi:10.3762/bjoc.22.51

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Perspective
Published 30 Apr 2026

Photoorganocatalytic trifluoromethylation of (het)arenes in green conditions

  • Egor N. Boronin,
  • Svetlana E. Kaurkina,
  • Milena M. Svetlakova,
  • Anton S. Bolshakov,
  • Maxim V. Arsenyev,
  • Vasilii F. Otvagin,
  • Alexey Yu. Fedorov,
  • Timothy Noël and
  • Alexander V. Nyuchev

Beilstein J. Org. Chem. 2026, 22, 662–671, doi:10.3762/bjoc.22.50

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Published 30 Apr 2026

Advantages of PROTACs in achieving selective degradation of homologous protein families

  • Luxi Yang,
  • Xinfei Mao,
  • Jingyi Zhang,
  • Jing Shu,
  • Wenhai Huang,
  • Xiaowu Dong,
  • Yinqiao Chen and
  • Mingfei Wu

Beilstein J. Org. Chem. 2026, 22, 628–661, doi:10.3762/bjoc.22.49

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Published 27 Apr 2026

Hydrogen production from formic acid catalyzed by NHC–Cu complexes

  • Orlando Santoro and
  • Catherine S. J. Cazin

Beilstein J. Org. Chem. 2026, 22, 620–627, doi:10.3762/bjoc.22.48

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Published 23 Apr 2026

Towards the targeted protein degradation of CK2: design and synthesis of CAM4066-based PROTACs

  • Sophie Day-Riley,
  • Sona Krajcovicova,
  • Aryaman Raj Sokhal,
  • Jan L. Venne,
  • Paul Brear,
  • Marko Hyvönen,
  • Benjamin C. Whitehurst,
  • Jason S. Carroll and
  • David R. Spring

Beilstein J. Org. Chem. 2026, 22, 611–619, doi:10.3762/bjoc.22.47

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Published 22 Apr 2026
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