Synthesis and anti-cancer activity of naphthalimide–organylselanyl conjugates

• Rajkumar Ravi and
• Selvakumar Karuthapandi

Beilstein J. Org. Chem. 2026, 22, 416–435, doi:10.3762/bjoc.22.29

• epidermal growth factor receptor (EGFR) in which erlotinib, a well-known anticancer drug, binds. Keywords: cell line study; density functional theory; MDA-MB-231; molecular docking; organoselanyl conjugates; Introduction Cancer remains one of the most common and life-threatening diseases globally, posing

• receptor, further studies are required to understand the extent of specificity towards the targets. Conclusion The selenium-incorporated naphthalimide–organoselanyl conjugates, selenides 7 and 8, were extensively characterised using various spectroscopic and analytical techniques, and the molecular