Unsymmetrical sulfoxides with sterically hindered catechol fragment: synthesis, structure, electrochemical properties, and antiradical activity

• Daria A. Burmistrova,
• Vasiliy A. Fokin,
• Oleg P. Demidov,
• Mikhail A. Kiskin,
• Maxim V. Arsenyev,
• Andrey I. Poddel’sky,
• Nadezhda T. Berberova and
• Ivan V. Smolyaninov

Beilstein J. Org. Chem. 2026, 22, 828–837, doi:10.3762/bjoc.22.65

• reaction (Scheme 1) [23][42]. When converting these thioethers into sulfoxides using hydrogen peroxide as the oxidant, there is a risk of concurrent oxidation of the catechol moiety. The oxidation of 3,5-di-tert-butylcatechol (3,5-DTBC) by hydrogen peroxide is a classic reaction in bioinorganic chemistry

Radical ligand transfer: a general strategy for radical functionalization

• David T. Nemoto Jr,
• Kang-Jie Bian,
• Shih-Chieh Kao and
• Julian G. West

Beilstein J. Org. Chem. 2023, 19, 1225–1233, doi:10.3762/bjoc.19.90

• development. Outside of bioinorganic chemistry, the concept of radical ligand transfer was investigated in early work by Jay Kochi in purely synthetic systems (Scheme 1) [26][27]. Studies on the oxidation of alkyl radicals with earth abundant cupric salts uncovered the ability of simple Cu(II) chloride to

Incorporation of a metal-mediated base pair into an ATP aptamer – using silver(I) ions to modulate aptamer function

• Marius H. Heddinga and
• Jens Müller

Beilstein J. Org. Chem. 2020, 16, 2870–2879, doi:10.3762/bjoc.16.236

• function opens new possibilities for applications of oligonucleotides. Keywords: aptamer; ATP; bioinorganic chemistry; DNA; imidazole; metal-mediated base pairs; Introduction Aptamers are oligonucleotides capable of recognizing and binding to specific molecules up to the size of proteins [1]. While

Aqueous olefin metathesis: recent developments and applications

• Valerio Sabatino and
• Thomas R. Ward

Beilstein J. Org. Chem. 2019, 15, 445–468, doi:10.3762/bjoc.15.39

•  1c). This review focuses on the recent improvements of olefin metathesis in aqueous media and the resulting applications in bioinorganic chemistry and chemical biology. Review Challenges in aqueous metathesis The first examples of aqueous metathesis were reported in the late 1980s [25][26]. ROMP

Second generation silver(I)-mediated imidazole base pairs

• Susanne Hensel,
• Nicole Megger,
• Kristina Schweizer and
• Jens Müller

Beilstein J. Org. Chem. 2014, 10, 2139–2144, doi:10.3762/bjoc.10.221

• to a 50% larger increase in the melting temperature when a DNA duplex with methylated imidazole nucleosides is applied. This significant effect can likely be attributed to a better steric shielding of the metal ion within the metal-mediated base pair. Keywords: bioinorganic chemistry; DNA; imidazole

Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups

• H. Bauke Albada,
• Alina-Iulia Chiriac,
• Michaela Wenzel,
• Maya Penkova,
• Julia E. Bandow,
• Hans-Georg Sahl and
• Nils Metzler-Nolte

Beilstein J. Org. Chem. 2012, 8, 1753–1764, doi:10.3762/bjoc.8.200

• H. Bauke Albada Alina-Iulia Chiriac Michaela Wenzel Maya Penkova Julia E. Bandow Hans-Georg Sahl Nils Metzler-Nolte Inorganic Chemistry I – Bioinorganic Chemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Universitätsstraße 150, 44801 Bochum, Germany Institute for Medical

Synthesis of 2,6-disubstituted tetrahydroazulene derivatives

• Zakir Hussain,
• Henning Hopf,
• Khurshid Ayub and
• S. Holger Eichhorn

Beilstein J. Org. Chem. 2012, 8, 693–698, doi:10.3762/bjoc.8.77

• isomers 9 and 10. Acknowledgements Z. H. thanks Prof. Dr. Wolfgang Gärtner at the Max-Planck Institute for Bioinorganic Chemistry, Mülheim (Germany) for his support in purification and characterization all new substances in the present study.

Perhydroazulene-based liquid-crystalline materials with smectic phases

• Zakir Hussain,
• Henning Hopf and
• S. Holger Eichhorn

Beilstein J. Org. Chem. 2012, 8, 403–410, doi:10.3762/bjoc.8.44

• Information File 132: Additional material. Acknowledgements Z. H. thanks Prof. Dr. Wolfgang Gaertner at the Max-Planck Institute for Bioinorganic Chemistry, Muelheim (Germany), for his support to allow purification and characterization of all substances in the present study.