Rh-Catalyzed rearrangement of vinylcyclopropane to 1,3-diene units attached to N-heterocycles

• Franca M. Cordero,
• Carolina Vurchio,
• Stefano Cicchi,
• Armin de Meijere and
• Alberto Brandi

Beilstein J. Org. Chem. 2011, 7, 298–303, doi:10.3762/bjoc.7.39

• bond to form the intermediates C which can undergo metal hydride elimination or 1,3-hydride migration to the rhodium to give, respectively, the allyl- and alkylrhodium(III) hydride complexes D and F. Metal extrusion by reductive elimination leads to the observed dienes and regeneration of the catalyst

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

• Norio Shibata,
• Andrej Matsnev and
• Dominique Cahard

Beilstein J. Org. Chem. 2010, 6, No. 65, doi:10.3762/bjoc.6.65

• • radical generated from CF3I [40]. However, the reaction with bench-stable Togni’s reagent is mechanistically distinct from the previous radical approach (Scheme 34). In accord with a similar mechanism proposed by Togni [37], the resulting λ3-iodane species 40 undergo rapid reductive elimination with

C-Arylation reactions catalyzed by CuO-nanoparticles under ligand free conditions

• Mazaahir Kidwai,
• Saurav Bhardwaj and
• Roona Poddar

Beilstein J. Org. Chem. 2010, 6, No. 35, doi:10.3762/bjoc.6.35

• . The observed decrease in reactivity in the order p-nitroiodobenzene > iodobenzene > p-methyliodobenzene > 1-iodo-4-methoxybenzene suggests that the reaction proceeds by oxidative addition followed by reductive elimination. In addition to this, the order of reactivity suggests that aryl halides having

An exceptional P-H phosphonite: Biphenyl- 2,2'-bisfenchylchlorophosphite and derived ligands (BIFOPs) in enantioselective copper- catalyzed 1,4-additions

• T. Kop-Weiershausen,
• J. Lex,
• J.-M. Neudörfl and
• B. Goldfuss

Beilstein J. Org. Chem. 2005, 1, No. 6, doi:10.1186/1860-5397-1-6

• ligands (L*) exhibit large steric demands and good metal to ligand back bonding abilities. Such ligands generate active R-CuI-L* catalysts and support the rate determining reductive elimination in the catalytic cycle (Scheme 1). [42][43][44][45][46][47] Common basis for diol-based phosphoramidites and

• -rich transition metals, such as CuI. The rate determining reductive elimination was expected to be favored by the good metal to ligand back bonding properties of the σ*(P-Cl) acceptor as is well established in phosphites, i.e. σ*(P-OR), and phosphoramidites, i.e. σ*(P-NR2). Computed anharmonic CO