Beilstein J. Org. Chem.2006,2, No. 13, doi:10.1186/1860-5397-2-13
interest has been focused on new, highly-active classes of natural products such as the dolastatins and the cryptophycins. Such naturalcompounds and their synthetic derivatives have been evaluated for dosage and side effects in preliminary clinical trials [12][13][14][15], but the results do not suggest
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Graphical Abstract
Scheme 1:
Reagents and conditions for synthesis of N-glutaryl-deacetylcolchicine. The reagents used at each s...
Beilstein J. Org. Chem.2006,2, No. 12, doi:10.1186/1860-5397-2-12
ionic liquids for the synthesis of alkyl glycoside and disaccharides via coupling of thioalkyl glycosyl donors with glycal acceptors. Alkyl glycosides and oligosaccharides are important intermediates and products in the synthesis of biologically active naturalcompounds and mimics. For example, tetra-O