TY - JOUR A1 - Klásek, Antonín A1 - Lyčka, Antonín A1 - Křemen, Filip A1 - Růžička, Aleš A1 - Rouchal, Michal T1 - Molecular rearrangement of pyrazino[2,3-c]quinolin-5(6H)-ones during their reaction with isocyanic acid JF - Beilstein Archives Y1 - 2021/// SN - M3 - doi:10.3762/bxiv.2021.54.v1 N2 - A new tetrahydropyrazino[2,3-c]quinolin-5(6H)-ones were prepared from 3-chloroquinoline-2,4(1H,3H)-diones and ethylene diamine. In their reaction with HNCO, an unprecedented molecular rearrangement produced new types of hydantoin derivatives. All prepared compounds are characterized using their 1H, 13C, and 15N NMR spectra and the results of the X-ray analysis are also presented. A proposed mechanism of rearrangement is discussed in this essay. ER -